Nature

Chasing acyl carrier protein through a catalytic cycle of lipid A production

Figure 4: Molecular basis for the ordered-sequential reaction mechanism and involvement of ACP in lipid-product release. Site-directed mutants designed to alter Met 290 (Met290Cys), and His 239 ...
Medical Xpress

Hundreds of new N-acyl lipids identified, expanding the dictionary of human metabolism

Human metabolism is a complex web of chemical processes and interactions between our cells and the microbes living within us. The more scientists can identify and classify the molecules involved in ...
Science Daily

To make or to break: Novel reversible technique produces acyl fluoride using rare metal

Acyl fluorides are organic compounds that contain a fluorine atom in their structure. These compounds have recently gained much attention in transition-metal catalysis due to their stability and ...
The New England Journal of Medicine

Effect of ACAT Inhibition on the Progression of Coronary Atherosclerosis

The enzyme acyl–coenzyme A:cholesterol acyltransferase (ACAT) esterifies cholesterol in a variety of tissues. In some animal models, ACAT inhibitors have antiatherosclerotic effects. We performed ...
technologynetworks

Researchers Identify Hundreds of New N-Acyl Lipids

Human metabolism is a complex web of chemical processes and interactions between our cells and the microbes living within us. The more scientists can identify and classify the molecules involved in ...