Addiction decreases the brain’s ability to experience natural, healthy pleasure, driving increased cravings and compulsive substance use. But can this brain deficit be healed? New research from my lab ...

Scientists have recreated morphine-like pain relief in mice with a targeted therapy that avoids addiction-linked brain ...

Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal—driving ...

Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal-driving ...

Alcohol does not simply relax the mind. It rewires it. With repeated use, drinking can splinter the brain’s carefully ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...

Within the brain, chemical neurotransmitters like dopamine and norepinephrine regulate mood, emotions and many physiological and behavioral processes. Their imbalance can contribute to anxiety, ...

An international research team led by the Universitat Jaume I (UJI) has shown that the cerebellum, contrary to what was thought, fulfils functions that go beyond the motor sphere and can be ...

Researchers at Karolinska Institutet in Sweden have identified a brain circuit that can drive repetitive and compulsive behaviours in mice, even when natural rewards such as food or social contact are ...

A medication currently used to treat diabetes and obesity may offer a new way to help people struggling with alcohol ...