Endothelial cells are important players in promoting the microvascular disease that defines some of the pathologic lesions of diabetic nephropathy. Endothelial cell expression of intercellular ...

The role of integrins in muscle differentiation was addressed by ectopic expression of integrin α subunits in primary quail skeletal muscle, a culture system particularly amenable to efficient ...

DUBLIN--(BUSINESS WIRE)--The "Integrin Alpha 4 (CD49 Antigen Like Family Member D or VLA4 Subunit Alpha or CD49d or ITGA4) - Pipeline Review, H1 2019" drug pipelines has been added to ...

The anti-α4-integrin monoclonal antibody natalizumab (Tysabri) is effective in most patients in treating multiple sclerosis (MS), but a percentage of people develop infusion reactions or stop ...

This is a preview. Log in through your library . Abstract Integrin α/β heterodimer adopts a compact bent conformation in the resting state, and upon activation undergoes a large-scale conformational ...