Nature

Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method

Several antimalarial drugs are known to prolong ventricular repolarization as evidenced by QT/QTc interval prolongation. This can lead to Torsades de Pointes, a potentially lethal ventricular ...
Nature

QTc Interval in Infants Receiving Cisapride

OBJECTIVE: To examine the effect of cisapride on the corrected QT (QTc) interval in infants over a 14-day period. STUDY DESIGN: A prospective cohort study of infants receiving cisapride (0.8 mg/kg per ...
Medscape

QTc Prolongation and Risk of Sudden Cardiac Death: Is the Debate Over?

February 3, 2006-- A recent analysis of the prospective, population-based Rotterdam Study found that prolongation of the heart-rate corrected QT (QTc) interval increased the risk of sudden cardiac ...
BMJ

QTc: how long is too long?

Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA Correspondence to Dr M J Ackerman, Long QT Syndrome Clinic and the Mayo Clinic Windland Smith ...
ascopubs.org

Trials and Tribulations of Corrected QT Interval Monitoring in Oncology: Rationale for a Practice-Changing Standardized Approach

One of the principal tasks of an oncologist is to determine whether to administer, reduce the dose, or hold chemotherapy on the basis of patient characteristics, organ function, and toxicities. These ...
BMJ

QT INTERVALS IN ATHLETES

Aim To determine factors affecting the QT interval in athletes and find an improved means of QT correction (QTc) Method Data was gathered from the CAYA (Cardiovascular Assessment in Young Athletes) ...