Industry is adapting to the increasing complexity and poor solubility and bioavailability of molecules in the pipeline. Poor solubility and low bioavailability have hindered the development pipeline ...
Background and Objective: Narcotic analgesics such as hydromorphone undergo an extensive first-pass effect resulting in a low systemic bioavailability following oral administration. Alternative dosing ...
Objective: To assess magnesium enteral absorption from a magnesium-rich mineral water. Design: Experimental study. Setting: Department of Nuclear Medicine, Brugmann Hospital, Brussels, Belgium.
Please provide your email address to receive an email when new articles are posted on . Teriparatide administered through the RT-102 pill provided higher bioavailability than injection with no ...
Gerry McNally is the vice president of research and development at NextEvo Naturals and a seasoned consumer health care R&D executive with a track record of leading the conception, development and ...
MELBOURNE, Australia, Nov. 24, 2025 (GLOBE NEWSWIRE) -- Gelteq Limited (“Gelteq” or the “Company”), a clinical and science-based company specialising in gel-based oral delivery solutions, today ...
Objective: To measure the bioavailability of selenium from cooked and raw fish in humans by estimating and comparing apparent absorption and retention of selenium in biosynthetically labelled fish ...
Announcing a new article publication for BIO Integration journal. Nitrofurantoin is a BCS II drug with a low solubility and dissolution rate. Therefore, the pharmaceutical applications of ...
Model-based formulation and technology selection methodologies facilitate rapid product development. A large percentage of new chemical entities (NCEs) have physicochemical properties that require ...
During early germination, water uptake activates metabolic pathways that stimulate the production of hydrolytic enzymes like ...
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