Cinchona alkaloids have a long and storied history in chemistry. Derived from Cinchona plants, members of the molecular family include the chiral catalyst cinchonidine and quinine, an early ...

Characteristic features of plants, such as their active ingredients or flower color, may have developed through very ...

Researchers mapped the full biosynthesis of quinine in cinchona trees, identifying key enzymes and intermediates. The ...

Cysteine biosynthesis is a vital biochemical process that converts inorganic sulphur into organic forms, ultimately producing the sulphur‐containing amino acid cysteine. This amino acid is essential ...

For over 350 years, quinine and other extracts from the cinchona tree (Cinchona spp.) were the only effective medicines ...

The widely used chemotherapy drug paclitaxel, commonly known as Taxol, was first extracted from the Pacific yew tree in 1963. But while plants have figured out how to manufacture the molecule, for ...

When cells utilize glucose as a carbon source, the HBP functions normally, maintaining intracellular O-GlcNAcylation at a high level. In this state, O-GlcNAc-modified SNAP25 stabilizes its interaction ...

Researchers identify the crucial protein for controlling the biosynthesis of steroidal glycoalkaloids and saponins in plants of the genus Solanum and for the first time demonstrate the ecological role ...

Scientists in China have developed a way to synthesize medicarpin in yeast—specifically, Saccharomyces cerevisiae, also known as baker’s yeast. Like paclitaxel in the 1990s, this tumor-attacking ...

Amyris. has filed a patent for methods to efficiently produce isoprenoids using biosynthetic pathways, nucleic acids, enzymes, vectors, and genetically modified host cells. The patent also covers ...