Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...

Q: My platelets were slightly elevated on my blood test. What can cause this? A: Platelets are part of how our body forms clots to stop bleeding. They are produced in the bone marrow by cells called ...

COVID-19 triggers hyperactivity in platelets leading to the formation of more blood clots in some patients. Photo credit: Getty Images Changes in blood platelets triggered by COVID-19 could contribute ...

Managing drug dosage is critical to the overall success of pharmaceutical intervention, not only in the clinic but also in clinical trials. Inadequate dose management of certain drugs can have fatal ...

Intravital microscopy image from the liver of a mouse model: a platelet (turquoise) adheres to the inflamed vessel wall (yellow dashed outline) and sheds a long, filamentous membrane extension—a ...