Peter Searson is leading a Johns Hopkins University team that is unravelling how Alzheimer's and other diseases disrupt the blood-brain barrier, the complex interface that allows or blocks the passage ...

Our brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and keeping harmful things out, such as bugs that can cause infection and toxins ...

“If we want to address BBB dysfunction, we have to have a good human BBB model,” said Ziyuan Guo, a neurobiologist and stem cell scientist at Cincinnati Children's Hospital Medical Center. “The whole ...

Antiamyloid antibodies have been used to reduce cerebral amyloid-beta (Aβ) load in patients with Alzheimer’s disease. We applied focused ultrasound with each of six monthly aducanumab infusions to ...

The cells that line the blood vessels in our brains are highly selective. By deciding which molecules are allowed in and out of our most important organ, the barrier these cells form is critical for ...

A study recently published in Nature has identified a key factor in the age-related breakdown of the blood-brain barrier (BBB) and has demonstrated that this damage may be reversible, potentially ...

Major advance promises to accelerate the understanding and improved treatment of a wide range of brain disorders, including stroke, cerebral vascular disorders, brain cancer, Alzheimer's disease, ...