When we think about iron imbalance, most people are familiar with iron deficiency and the health problems it can cause. What ...

Patients with serum ferritin levels higher than 1000 μg/L show a 91% increased risk for any fracture, with a doubled risk for vertebral and humerus fractures compared with those without iron overload.

USC researchers have uncovered a hidden driver behind the early and severe onset of Alzheimer's in people with Down syndrome: iron overload in the brain. Their study revealed that individuals with ...

The need for regular blood transfusions, as well as underlying processes in MDS, can result in iron overload. If left untreated, excess iron can cause widespread damage to organs throughout the body.

Patients with iron overload — serum ferritin > 1000 µg/L or a diagnosis of hemochromatosis or thalassemia — were 60% more likely to have an osteoporotic fracture during an up to 10-year follow-up than ...

BMP, bone morphogenetic protein; BMPR, bone morphogenetic protein receptor; HAMP, hepcidin; HFE, hereditary hemochromatosis protein; HJV, hemojuvelin; Holo-Tf, holo ...

New evidence suggests that trapping iron in unusable forms may starve vulnerable neurons, challenging decades of thinking about iron toxicity in Parkinson’s disease and opening new therapeutic ...

β-Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin, leading to ineffective erythropoiesis and severe anemia. Patients with ...

BERLIN—Kidney transplant recipients who have iron overload are at increased risk for bacterial infection compared with those who have normal iron levels, according to preliminary results of a Spanish ...