Some scientists believe that toxic tau fibrils hop between synapses to spread throughout the brain, prompted by Aβ aggregates and overactive neurons. New imaging and biomarker data add weight to this ...

Exploring the genetic blueprint of cerebrospinal fluid proteins, this study uncovers new markers and therapeutic targets that may unlock advancements in Alzheimer’s diagnosis and care. Study: ...

More than any other biofluid, the cerebrospinal fluid is in intimate contact with the brain. What can the thousands of proteins churning within this brain bath tell us about how Alzheimer’s develops, ...