The type 1 ryanodine receptor (RyR1) is an important calcium release channel in skeletal muscles essential for muscle contraction. It mediates calcium release from the sarcoplasmic reticulum, a ...
A subunit of voltage-gated calcium channels was found to have a functional role in T-cells, according to a Northwestern Medicine study published in Nature Communications. The findings add to a growing ...
A new study from Yale School of Medicine has shown that the neurons that generate higher cognition, and are a target of pathology in Alzheimer's disease and mental disorders such as schizophrenia, ...
Clusters of proteins found on neurons are calcium-signaling “hotspots” that link electrical signals to gene expression, allowing neurons to produce crucial proteins. The discovery may potentially lead ...
Researchers at Texas A&M Health and collaborators have developed engineered CRAC channel inhibitory binders that can ...
Pretein design researcher Yulai Liu holds an enlarged 3D printed model from his team's efforts to design functioning calcium channels entirely from scratch. He is standing in David Baker's lab at the ...
In a recent study posted to the bioRxiv* preprint server, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium ...
The design of new calcium channels, built bottom-up from scratch, was reported last week in Nature. "Biochemists have been studying ion channels for decades and debating about how they work for almost ...
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