The pneumococcus undergoes spontaneous phase variation between an opaque and a transparent colony form. In an animal model of systemic infection following intraperitoneal inoculation of mice, the ...

To improve diagnostic options for pneumococcal pneumonia, an ELISA system was developed that can detect ⩽6 ng/ml capsular polysaccharide in serum. The test was limited to 39 serotypes causing >95% of ...

Please provide your email address to receive an email when new articles are posted on . Neisseria meningitidis is a gram-negative diplococcus, which like all gram-negative bacteria, possesses a ...

Antibody responses to the O-specific polysaccharide of Klebsiella pneumoniae were immunogenic, with cross-reactivity among related subtypes; however, capsule interference with O-specific ...

BOSTON & ST. LOUIS--(BUSINESS WIRE)--Omniose, a company developing polysaccharide conjugate vaccines against serious bacterial threats, has been awarded a $3.6 million grant for the development of a ...

Enzymes synthesizing the bacterial capsular polysaccharide (CP) are attractive antimicrobial targets. However, we lack critical information about the structure and mechanism of many of them. In an ...

Acinetobacter baumannii is a critical-priority, multidrug-resistant pathogen that poses a severe threat in hospitals worldwide. A key structure of these bacteria is the protective layer of complex ...