Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development instead of following a fixed program, as reported by researchers from Science ...
In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers have now discovered that these skeletal cells do not just differ in their developmental ...
Perlecan is a large heparan sulphate proteoglycan integral to the assembly, maintenance and mechanical responsiveness of cartilage. During embryonic and postnatal cartilage development, perlecan ...