Pragmatic clinical trials are designed to assess the effectiveness of interventions in routine care settings, maximising applicability to everyday practice while preserving sufficient methodological ...

Clinical trials are the irreplaceable engine of drug development and a bedrock of modern medicine, yet patient enrollment ...

“Our clinicians engage in research now. It’s the usual care of the patient, and we generate research information from it.” —Louis Fiore, VA Boston Healthcare System The workshop session on innovations ...

Weight-loss injections have been found less effective in real-life scenarios than in controlled lab settings, with usage patterns playing a significant role, according to new research. Semaglutide and ...

If researchers hope to lean on data from a single trial for therapeutic approval, it is important to communicate with the FDA ...

Thomas Laughren, director of the Food and Drug Administration’s (FDA’s) Division of Psychiatry Products, explained the FDA’s current policies and recommendations surrounding the relationship between ...

Composite endpoints combine multiple individual outcomes into a single measure to improve statistical power, reduce sample size and capture the multifaceted impact of interventions. They are ...

The most important benefit of participating in a clinical trial is that patients get early access to potentially new and successful treatments or screenings before the general public. (Karmanos Cancer ...

The US Food and Drug Administration (FDA) has released an extensive new guidance document that one of its top drug regulatory officials says is aimed at "greatly increase[ing] the likelihood that data ...

Women were generally excluded from clinical trials until the 1990s; in 1993, the NIH inclusion policy was codified into ...

CNSide Diagnostics will present data from the FORESEE trial showcasing the CNSide CSF Assay Platform’s utility in diagnosing and guiding clinical decision making for breast cancer and non-small cell ...

Prospective FORESEE trial of CNSide Cerebrospinal Fluid (CSF) Assay met key primary and secondary endpoints CNSide CSF Assay influenced clinical management decisions in over 90% of leptomeningeal ...