Motivated by the latest drug development regulatory guidance, such as the US Food and Drug Administration Modernization Act 2.0, academic and biopharmaceutical industry professionals are increasingly ...

A small molecule known as 10H-phenothiazine reduced the loss of motor neurons, the nerve cells that are lost in SMA, in ...

In this whitepaper, Sartorius discusses the need to replace animal testing with advanced in vitro human cell models for pharmaceutical, chemical, and cosmetic development as, with only 5-10% of ...

Biological assailants like fungi, bacteria, and viruses continuously test natural defenses that have evolved over millennia. Newer and stranger particles that originate from burning fuels, harmful ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

In a breakthrough for the advanced study of gut health, scientists have developed a 3D microscopic version of the human intestines condensed into a small chip about half the size of a five-cent coin.