Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

Microscopes are an important tool in biomedical research as it allows for detailed observation and imaging of tissues. Since biological materials are opaque by their nature, severe light scattering ...

Genoa (Italy), July 24, 2025 – Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered ...

descSPIM enables three-dimensional imaging of diverse tissues like neural cells and cancerous tumors. The widespread dissemination and adoption of descSPIM can accelerate biomedical discoveries. Three ...

A new tissue expansion method enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations. For biologists, ...

What is Scanning Ion Conductance Microscopy? Scanning Ion Conductance Microscopy (SICM) is a non-contact scanning probe microscopy technique that enables high-resolution imaging of living cells and ...

In 1922, French physicist Léon Brillouin predicted an interesting phenomenon – when light is shone on a material, it interacts with the naturally occurring thermal vibrations within it, exchanging ...

Cell mass and chemical composition are important aggregate cellular properties that are especially relevant to physiological processes, such as growth control and tissue homeostasis. Despite their ...

Robert Prevedel is a researcher at the European Molecular Biology Laboratory (EMBL; Heidelberg, Germany), whose lab focuses on developing light microscopy-based techniques for a variety of ...