Innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer. DNA is well-known for its double helix shape. But the human genome ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

A new comprehensive analysis has revealed that major depressive disorder alters both the physical architecture and the ...

This image depicts the detection of structural variants (SVs) at low sequencing coverage in both unique and repetitive regions by genomic proximity mapping (GPM), compared with other SV-calling ...

A major cardiovascular risk factor is thickening of the heart walls (hypertrophy), which can result from high blood pressure—but is also linked to inherited diseases of the heart which can lead to ...

Research co-led by King's College London and Sidra Medicine, Qatar, has produced the most detailed map to date of large-scale ...

Researchers from the Perelman School of Medicine at the University of Pennsylvania have invented a new way to map specific DNA markings called 5-methylcytosine (5mC) which regulate gene expression and ...

The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved. But DNA ...

The Cucurbitaceae family, comprising economically important crops such as cucumber, melon, and watermelon, exhibits remarkable phenotypic diversity in traits including fruit size, shape, and flesh ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...