Multicellular organisms, including humans, can be incredibly complex even though they start from one fertilized cell. The many cells that compose the tissues and organs in a body are derived from ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

Researchers at Tsinghua University have released a novel Python toolkit, scLT-kit, which automates the processing and analysis of single-cell lineage tracing data, delivering clear insights into how ...

The workflow of scLT-kit. Based on the time-series lineage tracing single-cell data (top left panel), scLT-kit calculates the barcoding fraction and clone sizes (top right panel, scLT-statistics ...

A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. “They are not identical,” said Magdalena Zernicka-Goetz, a ...