Endochondral bone development is the principal mechanism by which the vertebrate skeleton forms, involving the replacement of a transient cartilage template with mineralised bone. Mesenchymal cells ...

Endochondral bone regeneration mimics the natural process by which cartilage templates are formed and subsequently remodelled into bone. This developmental engineering approach relies on chondrogenic ...

A new study explores the potential of fibroblast growth factor receptor (FGFR) antagonists in restoring defective mandibular bone repair in mouse models of osteochondrodysplasia, a group of genetic ...

New research uncovers how the Clec14a protein in capillary endothelial cells controls bone growth and maturation, revealing a key mechanism in skeletal development. Study: Type-H endothelial cell ...