Elevated interferon levels are independently linked to key metabolic abnormalities in SLE, including dyslipidemia and pancreatic β‑cell dysfunction.

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory response. But it is just as important to resolve that inflammation and return ...

The value of nephrectomy in metastatic renal-cell cancer has long been debated. Several nonrandomized studies suggest a higher rate of response to systemic therapy and longer survival in patients who ...

We describe a case of life-threatening disseminated coccidioidomycosis in a previously healthy child. Like most patients with disseminated coccidioidomycosis, this child had no genomic evidence of any ...

Impact of protracted venous infusion fluorouracil with or without interferon alfa-2b on tumor response, survival, and quality of life in advanced colorectal cancer. The primary goal of this study was ...

Unlike antibody-producing B cells that help fight the current infection, the long-lived, non-circulating lung-BRMs migrate to the lungs from draining lymph nodes. They reside there permanently and lie ...

Interferons are medications that used to be standard treatments for hepatitis C. However, newer treatments called direct-acting antivirals (DAAs) are now the standard of care for treating hepatitis C.

The immune system depends on molecular alarms that detect danger inside cells. One of these alarms is STING, short for "stimulator of interferon genes." STING helps cells respond to infections, ...

If you caught a cold this past summer, it’s possible that the culprit was the adenovirus. Data from the Seattle Flu Study indicated that King County saw an uptick in adenovirus cases this summer ...