All bones start off as cartilage. Cartilage generates an abundant and specialized matrix surrounding its cells (extracellular matrix) that promotes the growth of skeletal structures and is pivotal in ...

Cell-based therapies could offer a way to treat cartilage injuries before the ultimate damage of osteoarthritis on articular cartilage. Cartilage-derived chondrocytes can be used for cartilage repair, ...

Cartilage injuries are a common clinical issue, often caused by trauma, severe infections, or degenerative joint diseases. The lack of direct blood supply to cartilage and limited access to nutrients ...

Researchers have designed a novel, hybrid hydrogel system to help address some of the challenges in repairing bone in the event of injury. A team of UConn Health researchers has designed a novel, ...

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to ...

Researchers in the United States and Japan have discovered a new mechanism that links age-related cartilage tissue stiffening with the repression of a key protein associated with longevity. These ...

Osteoarthritis (OA) is the most common form of degenerative joint disease in the world, affecting more than 27 million people in the US and costing nearly over two hundred billion dollars annually.

An unfortunate biological "feed-forward" loop drives cartilage cells in an arthritic joint to actually contribute to progression of the disease, say researchers at Duke University and Washington ...

Post-traumatic osteoarthritis (PTOA) is caused by joint injuries leading to progressive degeneration of articular cartilage. PTOA is prevalent in young adults and acute symptoms include swelling, ...

An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in the knee joints of old mice, a Stanford Medicine-led study has found. The treatment ...