Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by harnessing the body's immune system to target ...

Colorectal cancer breaks the usual immune rules, with certain regulatory T cells linked to improved survival. In many solid ...

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

As the immune system weakens with age, scientists have found a way to restore some of its lost strength. By delivering mRNA ...

Researchers at the Max Delbrück Center have found that a cellular housekeeping mechanism called autophagy plays a major role ...

As people grow older, their immune systems do not simply slow down, they often become locked into a simmering, ...

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ ...

One of the main changes is a loss of the innate immune system's naive T cells, the first line of defense against pathogens, and an increase in the adaptive immune system's memory T cells. This ...

Taken together, these advances suggest that part of age-related immune decline is driven by specific, potentially reversible ...