Enzymes known as kinases play a critical role in cell growth, metabolism and signaling in a multitude of organisms across the tree of life—from algae to helminths to mammals. Now, scientists have ...

Researchers have discovered that the kinase enzyme DAPK3 is elevated in triple-negative breast cancer cells where it regulates migration of the cancerous cells. The findings prompted the team to ...

The development of new therapeutics targeting protein kinases is crucial in the fight against diseases like cancer. Kinase drug discovery programs rely on the precise characterization and screening of ...

A recently published study from Fred Hutch Cancer Center dramatically expands the number of FDA-approved cancer drugs ...

Heart failure with preserved ejection function is a lethal form of heart failure, with few effective treatments. A team has now identified an enzyme, alpha-kinase 2 (ALPK2), that is specifically ...

In the human body, molecules known as kinases propagate signals within and between cells, relaying signals that allow cells to respond to changes in the environment. But there are hundreds of ...

Tatsuya Yoshida, Mikito Takefuji, and Toyoaki Murohara in the Department of Cardiology, Nagoya University Graduate School of Medicine, identified an enzyme, alpha-kinase 2 (ALPK2) that is specifically ...