90% of new molecules and roughly 40% of the top solid oral drugs marketed in the U.S. and Europe have generally low solubility. Hot-melt extrusion (HME) can help to overcome these challenges as the ...

You don't want to miss this! To permanently access this eBook for free, fill out the short form below. Developing oral solid dosage forms often comes with a critical challenge: improving the ...

In this brochure, Thermo Scientific takes a closer look at how integrated hot-melt extrusion (HME) workflows, paired with flexible downstream processing technologies from Thermo Fisher Scientific, can ...

Hot-melt extrusion (HME) has emerged as a game-changer in modern drug development—a solvent-free approach that transforms difficult compounds into effective medicines. This guide breaks down the ...

Injectable implants have distinct advantages for certain applications; for example, their efficacy over a long period of time can increase patient compliance, and the drug substance is applied in a ...

Pharmaceutics International, Inc. (Pii), has announced that it has added hot melt extrusion (HME) to its portfolio of formulation and process development solutions. The company has purchased a 16mm ...

SOMERSET, N.J., April 4, 2019 /PRNewswire-PRWeb/ -- Catalent Pharma Solutions, the leading global provider of advanced delivery technologies and development solutions for drugs, biologics and consumer ...