Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...
From small ions to large molecules, cellular gates control what can pass in and out of cells. But how one such gate, called pannexin-1 (PANX1), can handle vastly different cargo sizes has remained a ...
Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...
For biologists, seeing is believing. But sometimes biologists have a hard time seeing. One particularly vexing challenge is seeing all the molecules in an intact tissue sample, down to the level of ...
Why does cancer sometimes recur after chemotherapy? Why do some bacteria survive antibiotic treatment? In many cases, the answer appears to lie not in genetic differences, but in biological noise — ...