A hallmark of inflammatory diseases is the excessive recruitment and influx of monocytes to sites of tissue damage and their ensuing differentiation into macrophages. Numerous stimuli are known to ...

Monocytes patrol various tissues for signs of infection and inflammation. Inflammatory monocytes enter peripheral tissues at sites of microbial infection and differentiate into dendritic cells and ...

Scientists at The Wistar Institute discovered that Early Growth Response 1 (EGR1), a protein that turns on and off specific genes during blood cell development, inhibits expression of pro-inflammatory ...

Researchers at The Wistar Institute say they have discovered that Early Growth Response 1 (EGR1), a protein that turns on and off specific genes during blood cell development, inhibits expression of ...

Monocytes are a type of white blood cell that helps fight infections in your body. A high monocyte level may indicate inflammation, infection, blood disorders, and other health issues. Along with ...

Scientists discovered that EGR1inhibits expression of pro-inflammatory genes in macrophages. The discovery expands the understanding of how macrophages are set off and deactivated in the inflammatory ...

When the immune system mobilizes its troops, antigen-presenting cells play an important role. They can emerge from white blood cells (monocytes) that circulate in the blood. Scientists have now taken ...

Atypical amounts of these white blood cells are mainly caused by infection or a condition that affects your immune system. Treating the underlying condition can help raise or lower your monocyte ...

Your blood is made up of red blood cells, white blood cells, platelets, and plasma. White blood cells only make up about 1% of your blood, but they have an important function. As part of your immune ...

PHILADELPHIA -- (Jan. 13, 2021) -- Scientists at The Wistar Institute discovered that Early Growth Response 1 (EGR1), a protein that turns on and off specific genes during blood cell development, ...