Chemotherapy drugs that target cancer cells without damaging normal cells remain one of the key goals of precision medicine in cancer treatment. The challenge is designing drugs that do this ...

The field of cancer research has increasingly focused on the metabolic underpinnings of tumorigenesis, recognizing how the reprogramming of cellular energy ...

Researchers studied synthetic lethality pathway using Promega NanoBRET ® TE technology Study is the first to characterize uncompetitive binding directly in live cells, illuminating a mechanistic ...

BMS-986504, a first-in-class methylthioadenosine (MTA)-cooperative protein arginine methyltransferase 5 (PRMT5) targeting agent, showed promising antitumor activity in heavily pretreated patients with ...