Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

A 39-year-old woman presents to her community hospital concerned about tiny blood spots that cover most of her body. She explains that she has had muscle aches and has been feeling fatigued for the ...

Have you ever been in a classroom and wondered to yourself whether the information being presented could be wrong? During graduate school, I audited a medical school class in which the professor ...

Physical/chemical causes. These causes of hemolysis are most often secondary to improper handling of blood products. Reasons include inadvertent heating or freezing with subsequent thawing of the red ...

Clinicians who suspect their patients may have immune thrombocytopenia (ITP) should look for platelet autoantibodies both in the bloodstream and the bone marrow, new research suggests. "Diagnosing ITP ...

The most common etiology of pseudothrombocytopenia is platelet clumping induced by EDTA, which is the anticoagulant present in the purple tube in which blood is collected for a CBC. This clumping is ...

Thrombocytopenia, or a low platelet count, can impair blood clotting, potentially leading to severe bleeding from wounds. Underlying health conditions like autoimmune diseases and cancers, as well as ...

Thrombocytopenia is an autoimmune bleeding disorder in which the number of platelets in the blood is significantly lower than usual. The bone marrow produces platelets, which are blood cells that help ...

Medically reviewed by Doru Paul, MD Key Takeaways Myelosuppression is when bone marrow can't make enough blood cells.

Thrombocytopenia occurs when there aren’t enough platelets, which are tiny blood cells that help with clotting. In some cases, thrombocytopenia is the first sign of acute HIV infection. Severe ...