Platelets store and release CXCL12 (SDF-1), which governs differentiation of hematopoietic progenitors into either endothelial or macrophage-foam cells. CXCL12 ligates CXCR4 and CXCR7 and regulates ...

The usual job of the blood cells known as platelets is stopping bleeding. They rush to sites of vascular injury and signal other platelets to join them in forming blood clots. But circulating tumor ...

Future Microbiol. 2013;8(11):1431-1451. Bacterial contact with the platelets is a key event for the pathogenesis of sepsis, as deduced from the correlation between sepsis outcome and decreased ...

Researchers from Moscow Institute of Physics and Technology together with their colleagues from National Research Center for Hematology have developed a new method for assessing individual risks of ...

Abstract and Introduction Review of Normal Platelet Physiology and Megakaryocytopoisis Qualitative Platelet Abnormalities Conclusion References Nitric oxide (NO) is another drug used in the neonatal ...

When too many blood platelets stick together in the bloodstream, they form dangerous clots that can clog blood vessels and cause a heart attack. If a clot doesn't get dissolved or rapidly removed, it ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Macrothrombocytopenia (MTC) is a blood disorder in which blood cells called platelets are abnormally large. People with MTC also have thrombocytopenia, a low platelet count. MTC impairs blood clotting ...