While great strides have been made in exploring the world of RNA, mysteries remain—and one approach to solving them is to look at what exactly a strand of RNA is doing in a cell in real time. At a ...

Researchers often use antibodies to sort cell types in gene-expression studies. The standard way to confirm that cells have been sorted correctly is by fixing them for microscopy or lysing them for ...

In a recent study posted to the bioRxiv* preprint server, researchers elucidated the mechanism of ribonucleic acid (RNA) capping in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Study: ...

A team of researchers have developed an easy-to-use colorimetric assay for the detection of food contaminated with salmonella. The assay is based on a novel nucleic acid probe that is cleaved by an ...

The cold season is in full swing, throats are scratchy and noses are running. We feel ill and hope it is not the flu. The ...

A genetically encoded “live-cell” probe designed by researchers from Tokyo Tech has been able to identify phosphorylated Ser2 in the enzyme RNA polymerase II, subsequently identifying sites of the ...

Infection requires that SARS-CoV-2 slip into a cell, unnoticed by multiple alarms, and camouflage itself to resemble cellular genes and hijack the cell's machinery. To this end, the virus is equipped ...

Commercial-scale production of mRNA products is limited by their expense, complexity, and the high level of technical expertise required, which make them unsuitable for much of the world. A new ...

As RNA therapeutics evolve far beyond their vaccine origins, a new generation of scientists and manufacturers is rethinking how to produce these complex medicines safely, efficiently, and at scale.