Probes are short, single-stranded chains of nucleic acid that seek out and latch themselves to a complementary sequence of nucleic acids, often buried anonymously in a much larger section of DNA/RNA.

While great strides have been made in exploring the world of RNA, mysteries remain—and one approach to solving them is to look at what exactly a strand of RNA is doing in a cell in real time. At a ...

Researchers often use antibodies to sort cell types in gene-expression studies. The standard way to confirm that cells have been sorted correctly is by fixing them for microscopy or lysing them for ...

A team of researchers have developed an easy-to-use colorimetric assay for the detection of food contaminated with salmonella. The assay is based on a novel nucleic acid probe that is cleaved by an ...

SAN DIEGO--(BUSINESS WIRE)--TriLink BioTechnologies and Alphazyme, both part of Maravai LifeSciences, have collaborated to launch CleanScribe™ RNA Polymerase, a novel enzyme that reduces ...

Commercial-scale production of mRNA products is limited by their expense, complexity, and the high level of technical expertise required, which make them unsuitable for much of the world. A new ...

As RNA therapeutics evolve far beyond their vaccine origins, a new generation of scientists and manufacturers is rethinking how to produce these complex medicines safely, efficiently, and at scale.

A team led by UT Southwestern researchers has identified how SARS-CoV-2, the virus that causes COVID-19, builds a structure called the RNA cap that's critical for successful viral replication. The ...