Integration of a cDNA copy of the viral RNA genome is essential to establish infection by retroviruses. This process (see, for example, ref. 10 for a review) is catalysed by the virus-encoded enzyme ...

For almost a hundred years, retroviruses have been known to induce tumors. The field started with the discovery of avian erythroblastosis virus and Rous sarcoma virus, both of which cause tumors in ...