The breakthrough equips scientists with state-of-the-art tools to study complex tissue structures and cellular interaction. Credit: CI Photos via Shutterstock. · Medical Device Network · CI Photos via ...

A team of Harvard scientists and global collaborators has advanced spatial profiling technologies with a new workflow called ...

Spatial transcriptomics now spans two fundamentally different measurement strategies, and the choice between them shapes every downstream result a lab will generate. Sequencing-based platforms capture ...

Spatial transcriptomics has emerged as a powerful tool for in situ analysis of gene expression within tissues. However, current technologies still face several challenges, including high costs, ...

Ovarian clear cell carcinoma (OCCC) has a higher prevalence among East Asian women and is characterized by poor clinical ...

Spatial transcriptomics is revolutionizing the study of tissue architecture, cellular states, and tumor-immune interactions in clinical specimens. This presentation introduces the principles and ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

Tissue preparation is the step in spatial transcriptomics that can determine whether an experiment succeeds or fails before the sample ever reaches the instrument. Getting fixation, sectioning, and ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...