The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Human norovirus, a positive-strand RNA virus that is the leading cause of viral gastroenteritis accounting for an estimated 685 million cases and approximately 212,000 deaths globally per year, has no ...

The discovery could serve as a starting point for antiviral strategies. A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the ...

Nucleoside reverse transcriptase translocation inhibitors (NRTTIs) are a novel class of antiretroviral agents that inhibit HIV replication by targeting the viral reverse transcriptase enzyme and ...

The technology, called the Viral-Engineered RNA-based Activation System (VERAS), hijacks the virus's own replication machinery to switch on reporter or therapeutic genes precisely in infected cells.

Virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how our bodies detect and respond to viruses and viral replication. The publication explains ...

Single-cell analysis helps uncover how the BK virus replicates, opening the door to new drug targets. BK polyomavirus (BKPyV) is a major cause of kidney transplant failure. Without a complete ...