The research presented in the article delves into the regulatory role of the long non-coding RNA (lncRNA) ZNF593-AS in cardiac hypertrophy and myocardial remodeling, processes that are pivotal in the ...
UC Santa Cruz researchers have discovered a peptide in human RNA that regulates inflammation and may provide a new path for treating diseases such as arthritis and lupus. The team used a screening ...
While the human genome project revealed an unexpectedly small fraction of the genome dedicated to protein-coding genes, the ENCODE and related projects revealed that at least 70% of the genome is ...
A newly revealed role of lncRNAs in the deadly malaria parasite, Plasmodium falciparum, has opened new avenues for targeted therapeutic strategies. Malaria continues to be one of the most critical ...
In a paper in Cell Reports, Anindya Dutta, M.D., Ph.D., and colleagues detail the first structure-function study of a long non-coding RNA, or lncRNA, called MUNC lncRNA. Their findings point out the ...
A team from U of T Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell - a new approach to drug discovery that has already yielded some promising anti-inflammatory ...
Digital spatial profiling of advanced solid tumors and lymphomas from a phase 1 trial of copanlisib and nivolumab. Using single-cell sequencing to identify endothelial expression of immune checkpoint ...
Long non-coding RNAs (lncRNA) are sections of RNA over 200 nucleotides in length that are not translated into proteins, remaining in the nucleus following transcription in relatively low concentration ...
The lncRNA Workflow is an RT-qPCR workflow that is optimized for highly sensitive and specific quantification of long noncoding RNAs (lncRNAs) for gene expression analysis. The workflow provides a ...