DNA replication initiates from precise sites along the genome that are called replication origins. Prokaryotes and viruses generally replicate from a single origin, whereas, because of its complexity, ...
Figure 1: The DBF4 promoter locus contains a strong ori. Figure 2: Replication initiation at the DBF4 locus is largely confined to around 7 h after mitosis or 1 h after G1/S. Precise replication ...
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...
A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study by Weill Cornell Medicine researchers. The work, published Jan.
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...