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6:07
Primary Lateral Sclerosis. Primary Lateral Sclerosis (PLS) is a rare, slowly progressive neurodegenerative disorder characterized by the selective deterioration of upper motor neurons, leading to muscle weakness and stiffness, primarily affecting the legs and potentially the arms and speech/swallowing muscles. | Dr. Najeeb
25.9K views
Mar 9, 2025
Facebook
Dr. Najeeb
1:33
Case Study 209 | White Spots in the Brain A patient presents with slowly progressive neurologic symptoms - brain fog, slowed thinking, subtle movement changes-developing quietly over time. Imaging reveals symmetric white spots deep within the brain, in regions responsible for movement, coordination, cognition, and behavior. This pattern tells a story but it’s one that’s often overlooked unless you know exactly what to look for. What do you think the diagnosis is? Stay tuned tomorrow and I’ll exp
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9 months ago
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I have so many videos of Logan playing at the Harborside Fountain over the years. I was looking through them recently and realized just how much they show the progression of Sanfilippo. These videos span a little over five years. Logan is still mobile and still loves being on the go, but he has slowed down quite a bit. His balance has changed, his steps are less steady, and he needs more help than he used to. When you see him every day, the changes happen so gradually that sometimes you don't re
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