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0:59
YouTube
MedLecturesMadeEasy
Protamine reactions
Protamine sulfate is used to reverse effects of heparin anticoagulation Type I: HYPOTENSION Mediated by histamine release Caused by rapid admin of protamine causing systemic hypotension Treat with vasopressor support, slow protamine administration Type II: ANAPHYLAXIS Anaphylactoid / anaphylaxis Sx: systemic hypotension, increased airway ...
1.3K views
Sep 9, 2024
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Kristine Tuttle on Instagram: "Heparin and Warfarin are both anticoagulants that help prevent blood clots from forming or getting bigger by slowing down the body’s clotting process. 💉 Heparin Route: SUBQ or IV Onset: Rapid (Minutes) Safe in pregnancy Monitor: aPTT Antidote: Protamine Sulfate 💊Warfarin Route: Orally (PO) Onset: Slow (Hours) Not safe in pregnancy Monitoring: INR Antidote: Vitamin K #pharmacology #nurseinthemaking #nursingnotes #nursingschoolbundle"
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